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Drug Name | SGI-1776 |
Trade Name | |
Synonyms | |
Drug Descriptions |
SGI-1776 is a small molecule inhibitor of PIMs 1, 2, 3, and FLT-3, which may result in cell death via indirect inhibition of Mcl-1 transcription and protein synthesis (PMID: 21628411, PMID: 32558942). |
DrugClasses | PIM Inhibitor (Pan) 9 |
CAS Registry Number | 1025065-69-3 |
NCIT ID | C82404 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
INCB054329 + SGI-1776 | INCB054329 SGI-1776 | 0 | 0 |
Palbociclib + SGI-1776 | Palbociclib SGI-1776 | 1 | 0 |
Ruxolitinib + SGI-1776 | Ruxolitinib SGI-1776 | 1 | 0 |
SGI-1776 | SGI-1776 | 1 | 0 |