Welcome to CKB CORE's new home! Please be sure to update any bookmarks you may have.
×

Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name SGI-1776
Trade Name
Synonyms
Drug Descriptions

SGI-1776 is a small molecule inhibitor of PIMs 1, 2, 3, and FLT-3, which may result in cell death via indirect inhibition of Mcl-1 transcription and protein synthesis (PMID: 21628411, PMID: 32558942).

DrugClasses PIM Inhibitor (Pan) 9
CAS Registry Number 1025065-69-3
NCIT ID C82404

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
INCB054329 + SGI-1776 INCB054329 SGI-1776 0 0
Palbociclib + SGI-1776 Palbociclib SGI-1776 1 0
Ruxolitinib + SGI-1776 Ruxolitinib SGI-1776 1 0
SGI-1776 SGI-1776 1 0


Additional content available in CKB BOOST