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Drug Name | ETC-159 |
Trade Name | |
Synonyms | ETC-1922159 |
Drug Descriptions |
ETC-159 is a small molecule inhibitor of PORCN, which is demonstrated to suppress Wnt signaling and may result in inhibition of cell growth and lead to upregulation of genes related to cell differentiation (PMID: 26257057, PMID: 31391551). |
DrugClasses | WNT Inhibitor 16 |
CAS Registry Number | 1638250-96-0 |
NCIT ID | C123830 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ETC-159 | ETC-159 | 0 | 1 |
ETC-159 + Pembrolizumab | ETC-159 Pembrolizumab | 0 | 0 |