Ciforadenant
Drug Detail
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| Drug Name | Ciforadenant |
| Trade Name | |
| Synonyms | CPI-444|CPI 444|CPI444|V81444||V-81444 |
| Drug Descriptions |
Ciforadenant (CPI-444) is an antagonist of the adenosine receptor A2aR, which may relieve adenosine-mediated immune suppression and enhance antitumor activity (PMID: 29923026, PMID: 30131376). |
| DrugClasses | Adenosine Targeting 24 |
| CAS Registry Number | 1202402-40-1 |
| NCIT ID | C125659 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Atezolizumab + Ciforadenant | Atezolizumab Ciforadenant | 0 | 2 |
| Ciforadenant | Ciforadenant | 0 | 2 |
| Ciforadenant + CPI-006 | CPI-006 Ciforadenant | 0 | 1 |
| Ciforadenant + Daratumumab | Ciforadenant Daratumumab | 0 | 1 |
| Ciforadenant + Ipilimumab + Nivolumab | Ciforadenant Ipilimumab Nivolumab | 0 | 1 |
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