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| Drug Name | Daratumumab |
| Trade Name | Darzalex |
| Synonyms | JNJ-54767414 |
| Drug Descriptions |
Darzalex (Daratumumab) is a human antibody against CD38 that induces antibody-dependent cell-mediated cytotoxicity and complement-mediated cytotoxicity against CD38-positive tumor cells (PMID: 30546360). Darzalex (Daratumumab) is FDA approved for multiple myeloma patients as a monotherapy or in combination with lenalidomide and dexamethasone, or with bortezomib and dexamethasone, or with bortezomib, melphalan, and prednisone, or with pomalidomide and dexamethasone, or with bortezomib, thalidomide and dexamethasone (FDA.gov). |
| DrugClasses | CD38 Antibody 20 |
| CAS Registry Number | 945721-28-8 |
| NCIT ID | C74007 |
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