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Drug Name | GSK2830371 |
Trade Name | |
Synonyms | GSK-2830371 |
Drug Descriptions |
GSK2830371 is an allosteric, small molecule inhibitor of PPM1D, which results in increased phosphorylation Ppm1d substrates and may result in tumor growth inhibition (PMID: 24390428, PMID: 31136458). |
DrugClasses | PPM1D Inhibitor 3 |
CAS Registry Number | 1404456-53-6 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Carboplatin + GSK2830371 | Carboplatin GSK2830371 | 1 | 0 |
Cytarabine + GSK2830371 | Cytarabine GSK2830371 | 0 | 0 |
Doxorubicin + GSK2830371 | Doxorubicin GSK2830371 | 1 | 0 |
GSK2830371 | GSK2830371 | 2 | 0 |
GSK2830371 + Idasanutlin | GSK2830371 Idasanutlin | 0 | 0 |
GSK2830371 + Nutlin-3a | GSK2830371 Nutlin-3a | 0 | 0 |
GSK2830371 + Olaparib | GSK2830371 Olaparib | 0 | 0 |
GSK2830371 + Olaparib + Radiotherapy | GSK2830371 Olaparib Radiotherapy | 0 | 0 |