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| Drug Name | GSK2830371 |
| Trade Name | |
| Synonyms | GSK-2830371 |
| Drug Descriptions |
GSK2830371 is an allosteric, small molecule inhibitor of PPM1D, which results in increased phosphorylation Ppm1d substrates and may result in tumor growth inhibition (PMID: 24390428, PMID: 31136458). |
| DrugClasses | PPM1D Inhibitor 3 |
| CAS Registry Number | 1404456-53-6 |
| NCIT ID | NA |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + GSK2830371 | Carboplatin GSK2830371 | 1 | 0 |
| Cytarabine + GSK2830371 | Cytarabine GSK2830371 | 0 | 0 |
| Doxorubicin + GSK2830371 | Doxorubicin GSK2830371 | 1 | 0 |
| GSK2830371 | GSK2830371 | 2 | 0 |
| GSK2830371 + Idasanutlin | GSK2830371 Idasanutlin | 0 | 0 |
| GSK2830371 + Nutlin-3a | GSK2830371 Nutlin-3a | 0 | 0 |
| GSK2830371 + Olaparib | GSK2830371 Olaparib | 0 | 0 |
| GSK2830371 + Olaparib + Radiotherapy | GSK2830371 Olaparib Radiotherapy | 0 | 0 |