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Drug Name | G1T38 |
Trade Name | |
Synonyms | Lerociclib |
Drug Descriptions |
Lerociclib (G1T38) is a selective CDK4/6 inhibitor, which results in cell cycle arrest and tumor cell death (PMID: 32130619). |
DrugClasses | CDK4/6 Inhibitor 14 |
CAS Registry Number | 1628256-23-4 |
NCIT ID | C138165 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Enzalutamide + G1T38 | Enzalutamide G1T38 | 0 | 0 |
Fulvestrant + G1T38 | Fulvestrant G1T38 | 0 | 1 |
G1T38 | G1T38 | 0 | 0 |
G1T38 + G1T48 | G1T38 G1T48 | 0 | 0 |
G1T38 + Letrozole | G1T38 Letrozole | 0 | 2 |
G1T38 + Osimertinib | G1T38 Osimertinib | 0 | 1 |
G1T38 + SCH772984 | G1T38 SCH772984 | 0 | 0 |