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Drug Name | Cirmtuzumab |
Trade Name | |
Synonyms | UC-961 |
Drug Descriptions |
Cirmtuzumab (UC-961) is a monoclonal antibody that binds to human receptor tyrosine kinase-like orphan receptor 1 (ROR1) and blocks ROR1 signaling, leading to growth inhibition in tumor cells (PMID: 26297272, PMID: 29859176, PMID: 32090643). |
DrugClasses | ROR1 Antibody 7 |
CAS Registry Number | 1643432-38-5 |
NCIT ID | C118284 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Cirmtuzumab | Cirmtuzumab | 0 | 3 |
Cirmtuzumab + Docetaxel | Cirmtuzumab Docetaxel | 0 | 1 |
Cirmtuzumab + Ibrutinib | Cirmtuzumab Ibrutinib | 0 | 1 |
Cirmtuzumab + Paclitaxel | Cirmtuzumab Paclitaxel | 0 | 1 |
Cirmtuzumab + Venetoclax | Cirmtuzumab Venetoclax | 0 | 1 |