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Drug Name | VX-11e |
Trade Name | |
Synonyms | VX11e|VX 11e|VTX-11e|VRT-11E|VRT11E |
Drug Descriptions |
VX-11e is an ATP-competitive inhibitor of Mapk1 (Erk2) and Mapk3 (Erk1), which may result in growth inhibition and tumor regression (PMID: 19827834, PMID: 24265153, PMID: 31935908). |
DrugClasses | ERK Inhibitor (pan) 21 |
CAS Registry Number | 896720-20-0 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZ628 + VX-11e | AZ628 VX-11e | 0 | 0 |
Fulvestrant + VX-11e | Fulvestrant VX-11e | 0 | 0 |
Venetoclax + VX-11e | VX-11e Venetoclax | 1 | 0 |
VX-11e | VX-11e | 6 | 0 |
VX-11e + WEHI-539 | VX-11e WEHI-539 | 1 | 0 |