Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name WEHI-539
Trade Name
Synonyms
Drug Descriptions

WEHI-539 is a selective inhibitor of BCL-XL that stimulates apoptotic responses in cells, resulting in killing of tumor cells (PMID: 23603658, PMID: 32752193).

DrugClasses BCL-XL inhibitor 14
CAS Registry Number 1431866-33-9
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
A-1210477 + Lapatinib + WEHI-539 A-1210477 Lapatinib WEHI-539 0 0
A-1210477 + WEHI-539 A-1210477 WEHI-539 1 0
Alpelisib + WEHI-539 Alpelisib WEHI-539 1 0
Buparlisib + WEHI-539 Buparlisib WEHI-539 1 0
Dactolisib + WEHI-539 Dactolisib WEHI-539 5 0
G-TPP + WEHI-539 G-TPP WEHI-539 0 0
Sapanisertib + WEHI-539 Sapanisertib WEHI-539 1 0
Sirolimus + WEHI-539 Sirolimus WEHI-539 0 0
Torin 1 + WEHI-539 Torin 1 WEHI-539 1 0
Vistusertib + WEHI-539 Vistusertib WEHI-539 1 0
VX-11e + WEHI-539 VX-11e WEHI-539 1 0
WEHI-539 WEHI-539 0 0


Additional content available in CKB BOOST