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Drug Name AFM13
Trade Name
Synonyms AFM 13|AFM-13|Acimtamig
Drug Descriptions

AFM13 is a tetravalent bispecific antibody targeting CD30 and CD16A, which recruits CD16A-expressing NK cells to CD30-expressing tumor cells, potentially inducing tumor cell killing and enhanced antitumor immune response (PMID: 26231785, PMID: 33986022).

DrugClasses
CAS Registry Number 2738880-26-5
NCIT ID C94219

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Therapy Name Drugs Efficacy Evidence Clinical Trials
AB-101 + AFM13 AB-101 AFM13 0 1
AFM13 AFM13 0 3
AFM13 + Cyclophosphamide + Fludarabine AFM13 Cyclophosphamide Fludarabine 0 0
AFM13 + Pembrolizumab AFM13 Pembrolizumab 0 1


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