KPT-9274
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| Drug Name | KPT-9274 |
| Trade Name | |
| Synonyms | KCP-9274 |
| Drug Descriptions |
KPT-9274 is a dual inhibitor of PAK4 and NAMPT, which blocks the PAK4 and NAD pathways, possibly resulting in inhibition of tumor growth (PMID: 27390344, PMID: 31876149, PMID: 31795447). |
| DrugClasses | NAMPT Inhibitor 7 |
| CAS Registry Number | 1643913-93-2 |
| NCIT ID | C126646 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Adagrasib + KPT-9274 | Adagrasib KPT-9274 | 0 | 0 |
| KPT-9274 | KPT-9274 | 0 | 2 |
| KPT-9274 + Niacin | KPT-9274 Niacin | 0 | 1 |
| KPT-9274 + Sotorasib | KPT-9274 Sotorasib | 0 | 0 |
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