Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Drug Name | KPT-9274 |
Trade Name | |
Synonyms | KCP-9274 |
Drug Descriptions |
KPT-9274 is a dual inhibitor of PAK4 and NAMPT, which blocks the PAK4 and NAD pathways, possibly resulting in inhibition of tumor growth (PMID: 27390344, PMID: 31876149, PMID: 31795447). |
DrugClasses | NAMPT Inhibitor 7 |
CAS Registry Number | 1643913-93-2 |
NCIT ID | C126646 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Adagrasib + KPT-9274 | Adagrasib KPT-9274 | 0 | 0 |
KPT-9274 | KPT-9274 | 0 | 2 |
KPT-9274 + Niacin | KPT-9274 Niacin | 0 | 1 |
KPT-9274 + Sotorasib | KPT-9274 Sotorasib | 0 | 0 |