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Drug Name | SBI-0206965 |
Trade Name | |
Synonyms | |
Drug Descriptions |
SBI-0206965 is a small molecule that selectively inhibits ULK1, resulting in decreased phosphorylation of ULK1 targets, and potentially leading to increased tumor cell death in combination with mTOR inhibitors (PMID: 26118643, PMID: 30166400, PMID: 32393312). |
DrugClasses | |
CAS Registry Number | 1884220-36-3 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AZD8055 + SBI-0206965 | AZD8055 SBI-0206965 | 0 | 0 |
Cabozantinib + SBI-0206965 | Cabozantinib SBI-0206965 | 0 | 0 |
Crizotinib + SBI-0206965 | Crizotinib SBI-0206965 | 0 | 0 |
Regorafenib + SBI-0206965 | Regorafenib SBI-0206965 | 0 | 0 |
Sapanisertib + SBI-0206965 | SBI-0206965 Sapanisertib | 0 | 0 |
SBI-0206965 | SBI-0206965 | 0 | 0 |
SBI-0206965 + Sirolimus | SBI-0206965 Sirolimus | 0 | 0 |