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Drug Name | CX-072 |
Trade Name | |
Synonyms | CX072|CX 072|Pacmilimab |
Drug Descriptions |
CX-072 (Pacmilimab) is a prodrug consisting of a monoclonal antibody to PD-L1 (CD274) and a masking peptide that is cleaved by proteases specific to tumor cells (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3072-3072, PMID: 32681519). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | 2101273-62-3 |
NCIT ID | C132192 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CX-072 | CX-072 | 0 | 2 |
CX-072 + CX-2009 | CX-072 CX-2009 | 0 | 1 |
CX-072 + Ipilimumab | CX-072 Ipilimumab | 0 | 1 |
CX-072 + Vemurafenib | CX-072 Vemurafenib | 0 | 1 |