Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name CX-072
Trade Name
Synonyms CX072|CX 072|Pacmilimab
Drug Descriptions

CX-072 (Pacmilimab) is a prodrug consisting of a monoclonal antibody to PD-L1 (CD274) and a masking peptide that is cleaved by proteases specific to tumor cells (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3072-3072, PMID: 32681519).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121
CAS Registry Number 2101273-62-3
NCIT ID C132192

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
CX-072 CX-072 0 2
CX-072 + CX-2009 CX-072 CX-2009 0 1
CX-072 + Ipilimumab CX-072 Ipilimumab 0 1
CX-072 + Vemurafenib CX-072 Vemurafenib 0 1


Additional content available in CKB BOOST