CX-072
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| Drug Name | CX-072 |
| Trade Name | |
| Synonyms | CX072|CX 072|Pacmilimab |
| Drug Descriptions |
CX-072 (Pacmilimab) is a prodrug consisting of a monoclonal antibody to PD-L1 (CD274) and a masking peptide that is cleaved by proteases specific to tumor cells (Journal of Clinical Oncology 36, no. 15_suppl (May 20 2018) 3072-3072, PMID: 32681519). |
| DrugClasses | Immune Checkpoint Inhibitor 150 PD-L1/PD-1 antibody 132 |
| CAS Registry Number | 2101273-62-3 |
| NCIT ID | C132192 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| CX-072 | CX-072 | 0 | 2 |
| CX-072 + CX-2009 | CX-072 CX-2009 | 0 | 1 |
| CX-072 + Ipilimumab | CX-072 Ipilimumab | 0 | 1 |
| CX-072 + Vemurafenib | CX-072 Vemurafenib | 0 | 1 |
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