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Drug Name | RO6874281 |
Trade Name | |
Synonyms | RG 7461|RG7461|Simlukafusp alfa|RO-6874281 |
Drug Descriptions |
RO6874281 (Simlukafusp alfa) is a fusion protein consists of a human anti-fibroblast activation protein-alpha (FAP) antibody and an engineered interleukin-2, which may stimulate local immune response against FAP-positive tumor cells (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | 1776942-10-9 |
NCIT ID | C129383 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Atezolizumab + Bevacizumab + Obinutuzumab + RO6874281 | Atezolizumab Bevacizumab Obinutuzumab RO6874281 | 0 | 1 |
Atezolizumab + Obinutuzumab + RO6874281 | Atezolizumab Obinutuzumab RO6874281 | 0 | 1 |
Atezolizumab + RO6874281 | Atezolizumab RO6874281 | 0 | 2 |
Cetuximab + RO6874281 | Cetuximab RO6874281 | 0 | 0 |
Pembrolizumab + RO6874281 | Pembrolizumab RO6874281 | 0 | 1 |
RO6874281 | RO6874281 | 0 | 1 |