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Drug Name NIS793
Trade Name
Synonyms nisevokitug
Drug Descriptions

NIS793 is a monoclonal anti-transforming growth factor beta (TGF-beta) antibody that blocks TGF-beta signaling, leading to tumor growth inhibition (PMID: 31692434).

DrugClasses TGFB (Pan) Antibody 5
CAS Registry Number NA
NCIT ID C132250

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bevacizumab + Fluorouracil + Irinotecan + Leucovorin + NIS793 Bevacizumab Fluorouracil Irinotecan Leucovorin NIS793 0 1
Bevacizumab + Fluorouracil + Leucovorin + NIS793 + Oxaliplatin Bevacizumab Fluorouracil Leucovorin NIS793 Oxaliplatin 0 1
Fluorouracil + Irinotecan + Leucovorin + NIS793 + Oxaliplatin Fluorouracil Irinotecan Leucovorin NIS793 Oxaliplatin 0 2
Gemcitabine + Nab-paclitaxel + NIS793 Gemcitabine NIS793 Nab-paclitaxel 0 2
Gemcitabine + Nab-paclitaxel + NIS793 + Spartalizumab Gemcitabine NIS793 Nab-paclitaxel Spartalizumab 0 1
NIS793 NIS793 0 2
NIS793 + Sabatolimab NIS793 Sabatolimab 0 1
NIS793 + Spartalizumab NIS793 Spartalizumab 0 1


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