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Drug Name | APG-1252 |
Trade Name | |
Synonyms | BM-1252|Pelcitoclax|APG1252|APG 1252 |
Drug Descriptions |
Pelcitoclax (APG-1252) inhibits BCL2 and BCL-XL, which potentially leads to tumor growth inhibition (J Clin Oncol 40, no. 16_suppl (June 01, 2022) 9116). |
DrugClasses | BCL-XL inhibitor 14 BCL2 inhibitor 27 |
CAS Registry Number | 1619923-36-2 |
NCIT ID | C148488 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
APG-1252 | APG-1252 | 0 | 1 |
APG-1252 + Cobimetinib | APG-1252 Cobimetinib | 0 | 1 |
APG-1252 + Osimertinib | APG-1252 Osimertinib | 0 | 0 |
APG-1252 + Paclitaxel | APG-1252 Paclitaxel | 0 | 1 |