MIW815
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| Drug Name | MIW815 |
| Trade Name | |
| Synonyms | ADUS100|ADU-S100|NVP-MIW815 |
| Drug Descriptions |
MIW815 (ADUS100) is a synthetic cyclic dinucleotide that acts as an activator for the stimulation of interferon gene signaling (STING1), resulting in T cell differentiation and infiltration of the tumor, thereby possibly resulting in tumor regression (PMID: 28483787, PMID: 31355488). |
| DrugClasses | STING1 Agonist 21 |
| CAS Registry Number | 1638241-89-0 |
| NCIT ID | C125902 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Ipilimumab + MIW815 | Ipilimumab MIW815 | 0 | 1 |
| MIW815 | MIW815 | 0 | 1 |
| MIW815 + Pembrolizumab | MIW815 Pembrolizumab | 0 | 1 |
| MIW815 + Spartalizumab | MIW815 Spartalizumab | 0 | 1 |
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