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| Drug Name | SM08502 |
| Trade Name | |
| Synonyms | SM-08502|SM 08502|Cirtuvivint |
| Drug Descriptions |
SM08502 is a small molecule inhibitor of Wnt signaling that inhibits CDC-like kinase (CLK), potentially resulting in decreased tumor cell proliferation (PMID: 31560935, PMID: 39258426). |
| DrugClasses | WNT Inhibitor 17 |
| CAS Registry Number | 2143917-62-6 |
| NCIT ID | C142777 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Abiraterone + Prednisone + SM08502 | Abiraterone Prednisone SM08502 | 0 | 1 |
| Docetaxel + SM08502 | Docetaxel SM08502 | 0 | 1 |
| Fluorouracil + Irinotecan + Leucovorin + Panitumumab + SM08502 | Fluorouracil Irinotecan Leucovorin Panitumumab SM08502 | 0 | 1 |
| Olaparib + SM08502 | Olaparib SM08502 | 0 | 1 |
| SM08502 | SM08502 | 0 | 1 |
CKB BOOST