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Drug Name | CHIR-124 |
Trade Name | |
Synonyms | CHIR124 |
Drug Descriptions |
CHIR-124 is a selective inhibitor of CHK1, which may enhance sensitivity of tumor cells to chemotherapeutic agents (PMID: 17255282, PMID: 22244109). |
DrugClasses | CHK1 Inhibitor 18 |
CAS Registry Number | 405168-58-3 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Camptothecin + CHIR-124 | CHIR-124 Camptothecin | 2 | 0 |
CHIR-124 | CHIR-124 | 0 | 0 |
CHIR-124 + Gemcitabine | CHIR-124 Gemcitabine | 0 | 0 |
CHIR-124 + Irinotecan | CHIR-124 Irinotecan | 1 | 0 |
CHIR-124 + SN-38 | CHIR-124 SN-38 | 2 | 0 |