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| Drug Name | Obrindatamab |
| Trade Name | |
| Synonyms | MGD009|MGD-009|MGD 009 |
| Drug Descriptions |
Obrindatamab (MGD009) is an activating bispecific molecule that binds to both B7-H3 (CD276) and CD3, therefore bringing the targeted B7-H3-expressing cells together with T-cells, resulting in cytotoxic immune response (J Clin Oncol., 34 (no. 15_suppl): abstract TPS3105). |
| DrugClasses | CD276 Antibody 21 CD3 Antibody 119 |
| CAS Registry Number | 2069959-72-2 |
| NCIT ID | C136983 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Obrindatamab | Obrindatamab | 0 | 1 |
| Obrindatamab + Retifanlimab | Obrindatamab Retifanlimab | 0 | 1 |