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Drug Name SV-BR-1-GM
Trade Name
Synonyms Bria-IMT
Drug Descriptions

SV-BR-1-GM is a vaccine comprising hormone receptor-negative, ERBB2 (HER2)-positive breast cancer cells engineered to secrete GM-CSF, which may induce an antitumor immune response (PMID: 29867922).

DrugClasses
CAS Registry Number NA
NCIT ID C146711

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Cyclophosphamide + Interferon alpha-2b + Ipilimumab + SV-BR-1-GM Cyclophosphamide Interferon alpha-2b Ipilimumab SV-BR-1-GM 0 1
Cyclophosphamide + Interferon alpha-2b + Pembrolizumab + SV-BR-1-GM Cyclophosphamide Interferon alpha-2b Pembrolizumab SV-BR-1-GM 0 2
Cyclophosphamide + Interferon alpha-2b + SV-BR-1-GM Cyclophosphamide Interferon alpha-2b SV-BR-1-GM 0 1
Cyclophosphamide + Peg-interferon alfa-2a + Retifanlimab + SV-BR-1-GM Cyclophosphamide Peg-interferon alfa-2a Retifanlimab SV-BR-1-GM 0 1
Cyclophosphamide + Peg-interferon alfa-2a + SV-BR-1-GM Cyclophosphamide Peg-interferon alfa-2a SV-BR-1-GM 0 1
Cyclophosphamide + Retifanlimab + SV-BR-1-GM Cyclophosphamide Retifanlimab SV-BR-1-GM 0 0
SV-BR-1-GM SV-BR-1-GM 0 0


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