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Drug Name | LAM-002A |
Trade Name | |
Synonyms | Apilimod dimesylate|LAM 002A |
Drug Descriptions |
LAM-002A (Apilimod dimesylate) inhibits phosphatidylinositol-3-phosphate 5-kinase (PIKfyve), leads to inhibition of autophagy and subsequent tumor cell death (PMID: 28104689, Blood 2017 130 (Suppl 1):4119). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C126661 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ARQ 751 + LAM-002A | ARQ 751 LAM-002A | 1 | 0 |
LAM-002A | LAM-002A | 0 | 1 |
LAM-002A + MK2206 | LAM-002A MK2206 | 1 | 0 |