Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Drug Name | LAM-002A |
| Trade Name | |
| Synonyms | Apilimod dimesylate|LAM 002A |
| Drug Descriptions |
LAM-002A (Apilimod dimesylate) inhibits phosphatidylinositol-3-phosphate 5-kinase (PIKfyve), leads to inhibition of autophagy and subsequent tumor cell death (PMID: 28104689, Blood 2017 130 (Suppl 1):4119). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C126661 |
| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| ARQ 751 + LAM-002A | ARQ 751 LAM-002A | 1 | 0 |
| LAM-002A | LAM-002A | 0 | 1 |
| LAM-002A + MK2206 | LAM-002A MK2206 | 1 | 0 |