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Drug Name | ARQ 751 |
Trade Name | |
Synonyms | ARQ-751|ARQ751 |
Drug Descriptions |
ARQ 751 is an inhibitor of AKT1, AKT2, and AKT3, which may result in inhibition of the AKT/PI3K/MTOR pathway, thereby leading to tumor growth inhibition (PMID: 26469692). |
DrugClasses | Akt Inhibitor (Pan) 21 |
CAS Registry Number | NA |
NCIT ID | C128250 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ARQ 751 | ARQ 751 | 11 | 1 |
ARQ 751 + AZD0156 | ARQ 751 AZD0156 | 1 | 0 |
ARQ 751 + Fulvestrant | ARQ 751 Fulvestrant | 0 | 1 |
ARQ 751 + GSK2334470 | ARQ 751 GSK2334470 | 1 | 0 |
ARQ 751 + KU-57788 | ARQ 751 KU-57788 | 1 | 0 |
ARQ 751 + LAM-002A | ARQ 751 LAM-002A | 1 | 0 |
ARQ 751 + OSU-T315 | ARQ 751 OSU-T315 | 1 | 0 |
ARQ 751 + Paclitaxel | ARQ 751 Paclitaxel | 0 | 1 |
ARQ 751 + Sirolimus | ARQ 751 Sirolimus | 1 | 0 |
ARQ 751 + Torin 1 | ARQ 751 Torin 1 | 1 | 0 |