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Drug Name XmAb20717
Trade Name
Synonyms XmAb 20717|Vudalimab
Drug Descriptions

XmAb20717 (Vudalimab) is a bispecific antibody that targets both PD-1 (PDCD1) and CTLA4, potentially resulting in increased anti-tumor immune response (Journal for ImmunoTherapy of Cancer 2021;9).

DrugClasses CTLA4 Antibody 31 Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121
CAS Registry Number 2329669-72-7
NCIT ID C150463

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Abiraterone + Docetaxel + XmAb20717 Abiraterone Docetaxel XmAb20717 0 1
Abiraterone + XmAb20717 Abiraterone XmAb20717 0 1
Cabazitaxel + Carboplatin + XmAb20717 Cabazitaxel Carboplatin XmAb20717 0 1
Carboplatin + Pemetrexed Disodium + XmAb20717 Carboplatin Pemetrexed Disodium XmAb20717 0 1
Enzalutamide + XmAb20717 Enzalutamide XmAb20717 0 1
Olaparib + XmAb20717 Olaparib XmAb20717 0 1
Regorafenib + XmAb20717 Regorafenib XmAb20717 0 1
XmAb20717 XmAb20717 0 6


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