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Drug Name | RAF709 |
Trade Name | |
Synonyms | RAF-709 |
Drug Descriptions |
RAF709 is an ATP-competitive inhibitor that inhibits both BRAF monomers and RAF dimers, resulting in growth inhibition in tumor cells (PMID: 29343524). |
DrugClasses | BRAF Inhibitor 25 CRAF Inhibitor 12 |
CAS Registry Number | 1628838-42-5 |
NCIT ID | NA |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Binimetinib + RAF709 | Binimetinib RAF709 | 3 | 0 |
Dabrafenib + RAF709 + Trametinib | Dabrafenib RAF709 Trametinib | 2 | 0 |
Osimertinib + RAF709 | Osimertinib RAF709 | 0 | 0 |
Osimertinib + RAF709 + SCH772984 | Osimertinib RAF709 SCH772984 | 0 | 0 |
Osimertinib + RAF709 + Trametinib | Osimertinib RAF709 Trametinib | 0 | 0 |
RAF709 | RAF709 | 7 | 0 |
RAF709 + Selumetinib | RAF709 Selumetinib | 0 | 0 |
RAF709 + Trametinib | RAF709 Trametinib | 0 | 0 |