Drug Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Drug Name RAF709
Trade Name
Synonyms RAF-709
Drug Descriptions

RAF709 is an ATP-competitive inhibitor that inhibits both BRAF monomers and RAF dimers, resulting in growth inhibition in tumor cells (PMID: 29343524).

DrugClasses BRAF Inhibitor 25 CRAF Inhibitor 12
CAS Registry Number 1628838-42-5
NCIT ID NA

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Therapy Name Drugs Efficacy Evidence Clinical Trials
Binimetinib + RAF709 Binimetinib RAF709 3 0
Dabrafenib + RAF709 + Trametinib Dabrafenib RAF709 Trametinib 2 0
Osimertinib + RAF709 Osimertinib RAF709 0 0
Osimertinib + RAF709 + SCH772984 Osimertinib RAF709 SCH772984 0 0
Osimertinib + RAF709 + Trametinib Osimertinib RAF709 Trametinib 0 0
RAF709 RAF709 7 0
RAF709 + Selumetinib RAF709 Selumetinib 0 0
RAF709 + Trametinib RAF709 Trametinib 0 0


Additional content available in CKB BOOST