RAF709
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| Drug Name | RAF709 |
| Trade Name | |
| Synonyms | RAF-709 |
| Drug Descriptions |
RAF709 is an ATP-competitive inhibitor that inhibits both BRAF monomers and RAF dimers, resulting in growth inhibition in tumor cells (PMID: 29343524). |
| DrugClasses | BRAF Inhibitor 26 CRAF Inhibitor 12 |
| CAS Registry Number | 1628838-42-5 |
| NCIT ID | NA |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Binimetinib + RAF709 | Binimetinib RAF709 | 3 | 0 |
| Dabrafenib + RAF709 + Trametinib | Dabrafenib RAF709 Trametinib | 2 | 0 |
| Osimertinib + RAF709 | Osimertinib RAF709 | 0 | 0 |
| Osimertinib + RAF709 + SCH772984 | Osimertinib RAF709 SCH772984 | 0 | 0 |
| Osimertinib + RAF709 + Trametinib | Osimertinib RAF709 Trametinib | 0 | 0 |
| RAF709 | RAF709 | 7 | 0 |
| RAF709 + Selumetinib | RAF709 Selumetinib | 0 | 0 |
| RAF709 + Trametinib | RAF709 Trametinib | 0 | 0 |
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