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Drug Name Lifileucel
Trade Name Amtagvi
Synonyms LN-144|LN144|LN 144
Drug Descriptions

Amtagvi (lifileucel) is a preparation of tumor-infiltrating lymphocytes isolated and expanded from patient tumor tissue, which may demonstrate enhanced anti-tumor immune activity when re-introduced into patients (PMID: 33979178). Amtagvi (lifileucel) is FDA-approved for use in patients with previously treated unresectable or metastatic melanoma (FDA.gov).

DrugClasses
CAS Registry Number 2306267-74-1
NCIT ID C120552

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Aldesleukin + Lifileucel Aldesleukin Lifileucel 0 1
Cyclophosphamide + Fludarabine + Lifileucel + Pembrolizumab Cyclophosphamide Fludarabine Lifileucel Pembrolizumab 0 1
Lifileucel Lifileucel 0 7
Lifileucel + Pembrolizumab Lifileucel Pembrolizumab 0 2


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