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Drug Name | AZD4573 |
Trade Name | |
Synonyms | AZD-4573|AZD 4573 |
Drug Descriptions |
AZD4573 is a selective inhibitor of Cdk9 that suppresses Mcl1 expression thus leads to apoptosis in tumor cells (Cancer Res 2018;78(13 Suppl):Abstract nr 310, PMID: 32175313, PMID: 31699827). |
DrugClasses | CDK9 Inhibitor 21 |
CAS Registry Number | 2057509-72-3 |
NCIT ID | C153377 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Acalabrutinib + AZD4573 | AZD4573 Acalabrutinib | 0 | 1 |
AZD4573 | AZD4573 | 0 | 2 |
AZD4573 + Fulvestrant + Palbociclib | AZD4573 Fulvestrant Palbociclib | 0 | 0 |
AZD4573 + Palbociclib | AZD4573 Palbociclib | 0 | 0 |
AZD4573 + Venetoclax | AZD4573 Venetoclax | 0 | 0 |