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Drug Name | Acalabrutinib |
Trade Name | Calquence |
Synonyms | ACP-196 |
Drug Descriptions |
Calquence (acalabrutinib) selectively inhibits BTK, resulting in decreased B-cell receptor signaling, and potentially leading to decreased tumor cell proliferation (PMID: 27903679, PMID: 26957112). Calquence (acalabrutinib) is FDA approved for use in patients with mantle cell lymphoma, chronic lymphocytic leukemia or small lymphocytic lymphoma (FDA.gov). |
DrugClasses | BTK inhibitor 37 |
CAS Registry Number | 1420477-60-6 |
NCIT ID | C113442 |