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| Drug Name | TG-1801 |
| Trade Name | |
| Synonyms | NI-1701|TG1801|TG 1801 |
| Drug Descriptions |
TG-1801 (NI-1701) is a bispecific antibody that binds to CD47 and CD19 on B cells and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, potentially leading increased antitumor immune response and phagocytosis of tumor cells (PMID: 29743205, PMID: 35538512). |
| DrugClasses | CD19 Antibody 21 CD47 Antibody 31 Immune Checkpoint Inhibitor 149 |
| CAS Registry Number | NA |
| NCIT ID | C166137 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| TG-1801 | TG-1801 | 0 | 2 |
| TG-1801 + Ublituximab | TG-1801 Ublituximab | 0 | 2 |
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