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Therapy Name | TG-1801 |
Synonyms | |
Therapy Description |
TG-1801 (NI-1701) is a bispecific antibody that binds to CD47 and CD19 on B cells and blocks CD47 downstream signaling and subsequent activation of the SIRPa receptor on macrophages, potentially leading increased antitumor immune response and phagocytosis of tumor cells (PMID: 29743205, PMID: 35538512). |