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Drug Name | AK105 |
Trade Name | |
Synonyms | AK-105|AK 105|Penpulimab |
Drug Descriptions |
AK105 is a monoclonal antibody against CD274 (PD-L1) that inhibits binding to the PDCD1 (PD1) receptor, potentially resulting in enhanced anti-tumor immune response (PMID: 29932513). |
DrugClasses | Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 121 |
CAS Registry Number | 2350298-92-7 |
NCIT ID | C155879 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
AK105 | AK105 | 0 | 0 |
AK105 + Anlotinib | AK105 Anlotinib | 0 | 0 |
AK105 + Cisplatin + Gemcitabine | AK105 Cisplatin Gemcitabine | 0 | 1 |