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Drug Name | ETC-1907206 |
Trade Name | |
Synonyms | ETC-206|AUM001|AUM-001|ETC206|ETC 206 |
Drug Descriptions |
ETC-1907206 is an inhibitor of MAPK interacting serine/threonine kinases (MKNK1, MKNK2), which inhibits the phosphorylation of eIF4E to prevent inflammation and cell proliferation (PMID: 31343094, PMID: 29683667). |
DrugClasses | |
CAS Registry Number | 1464151-33-4 |
NCIT ID | C153262 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Dasatinib + ETC-1907206 | Dasatinib ETC-1907206 | 0 | 1 |
ETC-1907206 | ETC-1907206 | 0 | 1 |
ETC-1907206 + Irinotecan | ETC-1907206 Irinotecan | 0 | 1 |
ETC-1907206 + Pembrolizumab | ETC-1907206 Pembrolizumab | 0 | 1 |