Seclidemstat
Drug Detail
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| Drug Name | Seclidemstat |
| Trade Name | |
| Synonyms | SP2577|SP 2577|SP-2577 |
| Drug Descriptions |
Seclidemstat (SP-2577) is a reversible LSD1 (KDM1A) inhibitor that inhibits transcriptional function of EWS/ETS fusions, leading to anti-tumor activity (AACR Annual Meeting 2019, Abstract CT-109, PMID: 32649682). |
| DrugClasses | KDM1A Inhibitor 15 |
| CAS Registry Number | 1423715-37-0 |
| NCIT ID | C154328 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Azacitidine + Seclidemstat | Azacitidine Seclidemstat | 0 | 1 |
| Pembrolizumab + Seclidemstat | Pembrolizumab Seclidemstat | 0 | 1 |
| Seclidemstat | Seclidemstat | 0 | 2 |
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