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Drug Name | Iomab-B |
Trade Name | |
Synonyms | I 131 MOAB BC8|131-I Apamistamab|Iodine I 131-apamistamab |
Drug Descriptions |
Iomab-B (131-I apamistamab) comprises an antibody targeting CD45 conjugated to iodine 131 (I-131), which delivers I-131 to CD45-expressing cells, potentially resulting in increased death of CD45-expressing tumor cells (NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | 2097132-02-8 |
NCIT ID | C2527 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Anti-CD19CAR-CD28-CD3zeta-EGFRt T-cells + Iomab-B | Anti-CD19CAR-CD28-CD3zeta-EGFRt T-cells Iomab-B | 0 | 1 |
Fludarabine + Iomab-B | Fludarabine Iomab-B | 0 | 1 |
Iomab-B | Iomab-B | 0 | 0 |