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Drug Name | CART-EGFRvIII |
Trade Name | |
Synonyms | |
Drug Descriptions |
CART-EGFRvIII comprises autologous T-cells engineered with a lentiviral vector to express a chimeric antigen receptor that targets EGFRvIII-expressing tumor cells, which may have anti-tumor activity (PMID: 25696001, PMID: 28724573). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C117727 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
CART-EGFRvIII | CART-EGFRvIII | 0 | 0 |
CART-EGFRvIII + Pembrolizumab | CART-EGFRvIII Pembrolizumab | 0 | 1 |