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Drug Name ABBV-151
Trade Name
Synonyms ARGX-115|ABBV151|ABBV 151|ARGX 115|ARGX-115|ARGX115|Livmoniplimab
Drug Descriptions

ABBV-151 is a monoclonal antibody that targets the glycoprotein A repetitions predominant (GARP)-transforming growth factor beta 1 (TGFbeta1) complex, which prevents release of active TGF-beta1, potentially leading to antitumor activity (Journal for ImmunoTherapy of Cancer 2022;10).

DrugClasses
CAS Registry Number 2412004-88-5
NCIT ID C165684

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Therapy Name Drugs Efficacy Evidence Clinical Trials
ABBV-151 ABBV-151 0 1
ABBV-151 + Budigalimab ABBV-151 Budigalimab 0 3
ABBV-151 + Budigalimab + Carboplatin + Pemetrexed Disodium ABBV-151 Budigalimab Carboplatin Pemetrexed Disodium 0 1
ABBV-151 + Budigalimab + Cisplatin + Pemetrexed Disodium ABBV-151 Budigalimab Cisplatin Pemetrexed Disodium 0 1
ABBV-151 + Budigalimab + Pemetrexed Disodium ABBV-151 Budigalimab Pemetrexed Disodium 0 1
ABBV-151 + Carboplatin + Pemetrexed Disodium ABBV-151 Carboplatin Pemetrexed Disodium 0 0
ABBV-151 + Cisplatin + Pemetrexed Disodium ABBV-151 Cisplatin Pemetrexed Disodium 0 0


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