MK-0482
Drug Detail
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| Drug Name | MK-0482 |
| Trade Name | |
| Synonyms | MK 0482|MK0482 |
| Drug Descriptions |
MK-0482 binds to ILT3 and prevents binding of ILT-3 ligands, leading to inhibition of ILT-3 dependent signaling, which may lead to increased antitumor immune response (J Clin Oncol 42, 2024 (suppl 16; abstr 2046), NCI Drug Dictionary). |
| DrugClasses | |
| CAS Registry Number | NA |
| NCIT ID | C180610 |
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| Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
|---|---|---|---|
| Carboplatin + MK-0482 + Paclitaxel + Pembrolizumab | Carboplatin MK-0482 Paclitaxel Pembrolizumab | 0 | 1 |
| Carboplatin + MK-0482 + Pembrolizumab + Pemetrexed Disodium | Carboplatin MK-0482 Pembrolizumab Pemetrexed Disodium | 0 | 1 |
| MK-0482 | MK-0482 | 0 | 2 |
| MK-0482 + Pembrolizumab | MK-0482 Pembrolizumab | 0 | 2 |
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