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Drug Name | ATLCAR.CD30 cells |
Trade Name | |
Synonyms | CAR.CD30-expressing autologous T lymphocytes |
Drug Descriptions |
ATLCAR.CD30 cells are autologous T-lymphocytes engineered to express a chimeric antigen receptor (CAR) that targets TNFRSF8 (CD30), which may induce lysis of TNFRSF8 (CD30)-positive tumor cells (PMID: 32701411, NCI Drug Dictionary). |
DrugClasses | |
CAS Registry Number | NA |
NCIT ID | C116738 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
ATLCAR.CD30 cells | ATLCAR.CD30 cells | 0 | 4 |
ATLCAR.CD30 cells + ATLCAR.CD30.CCR4 cells | ATLCAR.CD30 cells ATLCAR.CD30.CCR4 cells | 0 | 1 |
ATLCAR.CD30 cells + Bendamustine + Fludarabine | ATLCAR.CD30 cells Bendamustine Fludarabine | 0 | 0 |
ATLCAR.CD30 cells + Cyclophosphamide + Fludarabine | ATLCAR.CD30 cells Cyclophosphamide Fludarabine | 0 | 2 |
ATLCAR.CD30 cells + Nivolumab | ATLCAR.CD30 cells Nivolumab | 0 | 1 |