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Drug Name Cosibelimab
Trade Name Unloxcyt
Synonyms CK-301|CK 301|TG-1501|TG1501|TG 1501|cosibelimab-ipdl
Drug Descriptions

Unloxcyt (cosibelimab) is a human monoclonal antibody against PD-L1 (CD274), which may block immune checkpoint, and lead to anti-tumor immune response (PMID: 37848259). Unloxcyt (cosibelimab) is FDA approved for use in adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma who are not candidates for curative surgery or curative radiation (FDA.gov).

DrugClasses Immune Checkpoint Inhibitor 149 PD-L1/PD-1 antibody 122
CAS Registry Number 2216751-26-5
NCIT ID C151947

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Carboplatin + Cosibelimab + Pemetrexed Disodium Carboplatin Cosibelimab Pemetrexed Disodium 0 1
Cisplatin + Cosibelimab + Pemetrexed Disodium Cisplatin Cosibelimab Pemetrexed Disodium 0 1
Cosibelimab Cosibelimab 0 2


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