Molecular Profile Detail

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Profile Name BRAF L597X
Gene Variant Detail

BRAF L597X (unknown)

Relevant Treatment Approaches

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Molecular Profile Indication/Tumor Type Response Type Relevant Treatment Approaches Therapy Name Approval Status Evidence Type Efficacy Evidence References
BRAF L597X melanoma sensitive Trametinib Guideline Actionable Mekinist (trametinib) is included in guidelines as second-line therapy for metastatic or unresectable cutaneous melanoma patients with BRAF L597 mutations (NCCN.org). detail...