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| Profile Name | KIT G565R KIT K642E |
| Gene Variant Detail | |
| Relevant Treatment Approaches |
| Molecular Profile | Indication/Tumor Type | Response Type | Relevant Treatment Approaches | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|---|
| KIT G565R KIT K642E | gastrointestinal stromal tumor | predicted - sensitive | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, Gleevec (imatinib) treatment resulted in a partial metabolic response in a patient with gastrointestinal stromal tumor in the prostate harboring KIT G565R and K642E (PMID: 39263341). | 39263341 |