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Therapy Name | FANG vaccine |
Synonyms | |
Therapy Description |
Vigil (FANG vaccine) is a combination of autologous tumor cells expressing recombinant human granulocyte macrophage-colony stimulating factor (GM-CSF) and RNAi against furin convertase. FANG stimulates cell maturation through GM-CSF and prevents GM-CSF degradation by Tgfb1 and Tgfb2 (PMID: 22186789). |