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Therapy Name EMB-07
Synonyms
Therapy Description

EMB-07 is a bispecific T-cell engager that targets ROR1 expressed on tumor cells and CD3, which potentially induces killing of tumor cells expressing ROR1 and leads to inhibition of tumor growth (Cancer Res (2024) 84 (7_Supplement): LB126).

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Drug Name Trade Name Synonyms Drug Classes Drug Description
EMB-07 EMB 07|EMB07 CD3 Antibody 99 ROR1 Antibody 7 EMB-07 is a bispecific T-cell engager that targets ROR1 expressed on tumor cells and CD3, which potentially induces killing of tumor cells expressing ROR1 and leads to inhibition of tumor growth (Cancer Res (2024) 84 (7_Supplement): LB126).

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries
NCT05607498 Phase I EMB-07 First in Human Study of EMB-07 in Locally Advanced/Metastatic Solid Tumors Recruiting AUS 1


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