Therapy Detail
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| Therapy Name | PT217 |
| Synonyms | |
| Therapy Description |
PT217 is a bispecific antibody that targets DLL3 and CD47, potentially resulting in enhanced tumor cell phagocytosis and inhibition of tumor growth (Cancer Res (2022) 82 (12_Supplement): 2908). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| PT217 | PT-217|PT 217 | CD47 Antibody 31 DLL3 Antibody 10 | PT217 is a bispecific antibody that targets DLL3 and CD47, potentially resulting in enhanced tumor cell phagocytosis and inhibition of tumor growth (Cancer Res (2022) 82 (12_Supplement): 2908). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05652686 | Phase I | PT217 | A Study of PT217 in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) | Recruiting | USA | 0 |
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