Therapy Detail
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| Therapy Name | BAY3563254 |
| Synonyms | |
| Therapy Description |
BAY3563254 comprises a PSMA inhibitor linked to the radionuclide Actinium-225, with an albumin domain for increased tumor uptake and a chelator for stable radiolabeling, which delivers radiation to PSMA-expressing tumor cells, potentially inhibiting tumor growth (Cancer Res (2024) 84 (7_Supplement): ND09). |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| BAY3563254 | BAY 3563254|225Ac-PSMA-Trillium | BAY3563254 comprises a PSMA inhibitor linked to the radionuclide Actinium-225, with an albumin domain for increased tumor uptake and a chelator for stable radiolabeling, which delivers radiation to PSMA-expressing tumor cells, potentially inhibiting tumor growth (Cancer Res (2024) 84 (7_Supplement): ND09). |
Filtering
- Case insensitive filtering will display rows if any text in any cell matches the filter term
- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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- Click on any column header arrows to sort by that column
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Use simple literal full or partial string matches
- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
- Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06217822 | Phase I | BAY3563254 | First-in-human Study of 225Ac-PSMA-Trillium (BAY 3563254) in Participants With Advanced Metastatic Castration-resistant Prostate Cancer (mCRPC) (PAnTHA) | Recruiting | GBR | CAN | BEL | 0 |
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