Therapy Detail
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| Therapy Name | Capecitabine + Cisplatin + IMU-131 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Capecitabine | Xeloda | R340 | Chemotherapy - Antimetabolite 14 | Xeloda (capecitabine) is an antimetabolite that when activated to 5-FU ultimately inhibits DNA synthesis and cell division (NCI Drug Dictionary). |
| Cisplatin | Platinol | CDDP | Chemotherapy - Platinum 7 | Platinol (cisplatin) is a platinum based chemotherapeutic, which is FDA approved for bladder, ovarian, and testicular cancers (NCI Drug Dictionary). |
| IMU-131 | HER-Vaxx|IMU131|IMU 131 | HER2 (ERBB2) Vaccine 14 | IMU-131 is a B-cell vaccine comprised of 3 ERBB2 (HER2) extracellular epitopes conjugated to CRM197 (PMID: 33879458), potentially inducing polyclonal antibody response and anti-proliferative activity (PMID: 28183282). |
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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