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Drug Name IMU-131
Trade Name
Synonyms HER-Vaxx|IMU131|IMU 131
Drug Descriptions

IMU-131 is a B-cell vaccine comprised of 3 ERBB2 (HER2) extracellular epitopes conjugated to CRM197 (PMID: 33879458), potentially inducing polyclonal antibody response and anti-proliferative activity (PMID: 28183282).

DrugClasses HER2 (ERBB2) Vaccine 14
CAS Registry Number NA
NCIT ID C128283

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Capecitabine + Cisplatin + IMU-131 Capecitabine Cisplatin IMU-131 0 0
Capecitabine + IMU-131 + Oxaliplatin Capecitabine IMU-131 Oxaliplatin 0 0
Cisplatin + Fluorouracil + IMU-131 Cisplatin Fluorouracil IMU-131 0 0
IMU-131 IMU-131 0 0
IMU-131 + Paclitaxel IMU-131 Paclitaxel 0 0
IMU-131 + Paclitaxel + Ramucirumab IMU-131 Paclitaxel Ramucirumab 0 1
IMU-131 + Pembrolizumab IMU-131 Pembrolizumab 0 1


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