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Drug Name | IMU-131 |
Trade Name | |
Synonyms | HER-Vaxx|IMU131|IMU 131 |
Drug Descriptions |
IMU-131 is a B-cell vaccine comprised of 3 ERBB2 (HER2) extracellular epitopes conjugated to CRM197 (PMID: 33879458), potentially inducing polyclonal antibody response and anti-proliferative activity (PMID: 28183282). |
DrugClasses | HER2 (ERBB2) Vaccine 14 |
CAS Registry Number | NA |
NCIT ID | C128283 |
Therapy Name | Drugs | Efficacy Evidence | Clinical Trials |
---|---|---|---|
Capecitabine + Cisplatin + IMU-131 | Capecitabine Cisplatin IMU-131 | 0 | 0 |
Capecitabine + IMU-131 + Oxaliplatin | Capecitabine IMU-131 Oxaliplatin | 0 | 0 |
Cisplatin + Fluorouracil + IMU-131 | Cisplatin Fluorouracil IMU-131 | 0 | 0 |
IMU-131 | IMU-131 | 0 | 0 |
IMU-131 + Paclitaxel | IMU-131 Paclitaxel | 0 | 0 |
IMU-131 + Paclitaxel + Ramucirumab | IMU-131 Paclitaxel Ramucirumab | 0 | 1 |
IMU-131 + Pembrolizumab | IMU-131 Pembrolizumab | 0 | 1 |