Therapy Detail
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| Therapy Name | Linvoseltamab + REGN7945 |
| Synonyms | |
| Therapy Description | |
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| Drug Name | Trade Name | Synonyms | Drug Classes | Drug Description |
|---|---|---|---|---|
| Linvoseltamab | REGN5458|REGN-5458|REGN 5458|Anti-BCMA/CD3 BiTE | CD3 Antibody 104 TNFRSF17 Antibody 22 | Linvoseltamab (REGN5458) is a bispecific antibody that binds to TNFRSF17 (BCMA) and CD3 with potential antitumor activity (Blood (2019) 134 (Supplement_1): 3176). | |
| REGN7945 | REGN-7945|REGN 7945 | CD38 Antibody 21 | REGN7945 is a bispecific antibody that targets CD38 and CD28, which potentially increases T-cell activation and cytotoxicity against tumor cells (Blood (2024) 144 (Supplement 1): 3283). |
Filtering
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- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
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| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|
Filtering
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- Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
- Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
- Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")
Sorting
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- Click on any column header arrows to sort by that column
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| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT06669247 | Phase Ib/II | Linvoseltamab Linvoseltamab + REGN7945 | A Study to Assess the Safety and Anti-Tumor Activity of REGN7945 in Combination With Linvoseltamab in Adult Participants With Relapsed/Refractory Multiple Myeloma | Recruiting | AUS | 0 |
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