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Drug Name Linvoseltamab
Trade Name
Synonyms REGN5458|REGN-5458|REGN 5458|Anti-BCMA/CD3 BiTE
Drug Descriptions

Linvoseltamab (REGN5458) is a bispecific antibody that binds to TNFRSF17 (BCMA) and CD3 with potential antitumor activity (Blood (2019) 134 (Supplement_1): 3176).

DrugClasses CD3 Antibody 99 TNFRSF17 Antibody 20
CAS Registry Number NA
NCIT ID C158504

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Therapy Name Drugs Efficacy Evidence Clinical Trials
Bortezomib + Dexamethasone + Linvoseltamab Bortezomib Dexamethasone Linvoseltamab 0 1
Carfilzomib + Dexamethasone + Linvoseltamab Carfilzomib Dexamethasone Linvoseltamab 0 1
Daratumumab + Dexamethasone + Linvoseltamab Daratumumab Dexamethasone Linvoseltamab 0 1
Dexamethasone + Lenalidomide + Linvoseltamab Dexamethasone Lenalidomide Linvoseltamab 0 1
Linvoseltamab Linvoseltamab 0 6


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